Review Article: Arachnoid Granulations: An Overview

Abstract

Arachnoid granulations are cerebrospinal fluid (CSF)-filled protrusions with meningothelial lining extending through a dural opening into the venous sinuses. These structures filter and drain the CSF into central venous circulation across a lining of arachnoid cells. Detection of defects in these regular fillings within intracranial dural sinuses decreases the erroneous diagnosis of the existence of an intrasinus pathological process. It is essential for clinicians as well as forensic pathologists to be aware of unusual intracranially morphologies existing, especially intrasinus arachnoid granulations, as it is significant for clinical diagnosis, accurate treatment, and even in the postmortem examination in determining the cause of death. This article aims to provide an overview of arachnoid granulations in the medical literature.